Clinical utility of whole exome sequencing in structural brain disorders

About the speaker

Dr Ahmet Okay Çağlayan is currently an Associate Professor of Medical Genetics in Turkey and clinical geneticist with specific interest in neurodevelopmental disorders. He has extensive experience in next-generation and high-throughput molecular genetics, with special focus on the use of homozygosity mapping and whole-exome sequencing in recessive forms of structural and functional abnormalities of the brain. He has successfully detected rare and somatic genetic variant identification in diverse range of diseases using high-throughput and next-generation genomics approaches at Yale. In the last seven years, he has published papers in Cell, Science, Nature, Nature Genetics, Am J Hum Genet, Brain and Neuron including one of the first successful applications of exome sequencing in the identification of genetic basis of recessive forms of structural abnormalities of the brain. He has served as a member of editorial boards, a reviewer in top-tier journals and conferences, and was invited to serve as a program committee member for international workshops and conferences as well. He established Medical Genetics Department and giving lectures to under and post graduate students, assisting in seminar groups or laboratories, and grading.